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Northern Italy’s sand flies carry a recurring Wolbachia lineage that databases do not yet match

Screening 1,937 sand flies found substantial natural Wolbachia occurrence, while 11 complete profiles from Phlebotomus perniciosus were identical and lacked an exact public-database match.

Evidence
Peer-reviewed
Geography
Northern Italy
System
Vector / peri-urban and rural habitats

WHAT THE EVIDENCE SAYS

Researchers screened 1,937 sand flies in 124 pools collected from 24 sites during 2023–2025. Overall Wolbachia prevalence was estimated at 38.7%, with strong year-to-year variation. Eleven complete MLST profiles, all from Phlebotomus perniciosus, belonged to Supergroup B and shared an identical profile that had no exact match in public databases.

WHY IT MATTERS / OUR READ

Natural symbiont surveillance can reveal biological structure that standard vector datasets miss. The result is a foundation for asking whether this lineage changes sand-fly reproduction or pathogen transmission, not evidence that it already provides a control tool.

CAVEATS / UNCERTAINTY

Prevalence was estimated from pooled samples and varied by year. The study characterized infection and phylogeny; it did not test effects on vector competence, pathogen transmission, survival or the feasibility of Wolbachia-based control.

SOURCE

Parasites & Vectors — primary study
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